Credeați că s-a terminat cu hormonii care ne împing catre mancare? Ei bine, greul abia urmează! Cel mai puternic dintre ei este leptina, secretat direct de celula adipoasa. In mod normal cu cât exista mai multa grasime, cu atat nivelul leptinei este mai mare iar creierul nostru intelege ca sunt suficiente rezerve si se opreste din mancat. Acesta e mecanismul direct, fiziologic. Insa mai exista si rezistenta la leptina si aici totul se complica:(
Pe lângă celula adipoasa, leptina se secreta si in timpul meselor. Cu cat o masa e mai bogata in dulciuri si fainoase, cu atat mai multa leptina in sange. Fiecare gustare, cat de mica, mai creste si ea nivelul leptinei. Stresul si lipsa somnului contribuie si ele la sinteza. Cu atat mai bine, am putea spune, cu cât mai multa leptina, ca atât mai putin mancat. Dar vai, e tocmai pe dos! La asa o avalanșa de secretie creierul devine confuz. Cand leptina băltește in sange celulele din hipotalamus devin insensibile, rezistente. Hipersecretia de leptina duce, paradoxal, la disparitia senzatiei de satietate si in final se ajunge in situatia ca de ce mananci, tot foame iti este. Pe masura ce receptorii la leptina devin insensibili, organismul face tot mai multa grasime crezand ca e nevoie de mai multa leptina:(
Solutia? Stati departe de gustări, ronțăieli si ciuguleli, mâncați doar la mesele principale si atunci doar când va este cu adevarat foame. Odata instalată rezistenta la leptina suntem pierduți, vom fi din ce in ce mai grași si mai înfometați!

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